Treating Irritable Bowel Syndrome and its Effects
Irritable bowel syndrome or its acronym (IBS) It is a digestive disorder that is clinically characterized by the association of intestinal pain and a change in the depositary cycle that can vary between constipation and diarrhea or both.
How serious is IBS?
IBS does not imply a greater probability of suffering cancer or shortens life, however, it can have a significant impact on the quality of life of those who suffer from it, sometimes greater than that of other diseases such as asthma, migraine or diabetes mellitus.
Who it affects?
In addition, it is one of the most frequent gastrointestinal disorders in addition to being the second cause of work absenteeism after the common cold almost 20% of the population experience symptoms of irritable bowel syndrome throughout his life although only 15% of Those affected consult a doctor for it.
One of the most frequent causes of this gastrointestinal disorder is caused by abnormal contractions of the colon and small intestine (hence the term spastic colon, which has sometimes been used to describe IBS). Vigorous contractions of the intestine can cause cramps, which are treated with antispasmodics and fiber (both would help regulate colon contractions).
Stress and anxiety
Stress and anxiety are very noticeable factors that affect and contribute to this disorder, people who consult the doctor for IBS are more likely to suffer from anxiety than those who do not consult.
Another cause is food intolerance, it can also cause IBS, to determine that the individual suffers from IBS for this cause tests are performed with their diet called the elimination diet that is eliminating common foods and Αγορα Viagra Στα Φαρμακεια from their daily diet. This should be prescribed and supervised by a nutritionist as it can cause a nutritional deficit and worsen the condition of the patient.
What researchers have to say
Many researchers believe that IBS is caused by an increase in visceral sensitivity (of internal organs) to normal sensations. This theory proposes that the nerves of the intestine have hyperactivity in patients with IBS, so normal amounts of gas or bowel movement are perceived by patients with IBS as excessive and painful.
The main symptom of Irritable Bowel Syndrome (IBS) is abdominal pain accompanied by changes in the frequency and / or consistency of bowel movements, presenting either episodes of diarrhea or constipation. It is a chronic disorder, characterized by periods of exacerbation that alternate with periods of remission of symptoms. Its prevalence is 5-15%, it is more common in young adults and begins to decrease after 50 years.
Abdominal pain can be diffuse or localized in lower hemiabdomen, of moderate intensity, which is relieved after defecation, respects sleep and usually begins its onset with the intake of some food. The symptoms included in the Rome IV criteria say the patient with IBS may present: abdominal distension, mucus in the stool, rectal tenesmus (feeling of not being satisfied after defecation) or stool leakage (fecal incontinence), anal pain, early satiety when eating, nausea, vomiting, chest pain, and flatulence.
Depression and IBS
With a high frequency, the symptoms get worse after psychological alterations such as anxiety, depression, anguish, and stressful events. There are other extraintestinal symptoms that can accompany IBS such as painful rules, headache, urination, muscle and bone pain, and fatigue. To treat IBS, you should contact a specialist to be the one who prescribes the following medications that help to counteract the pain of IBS, it should be noted that this is a disorder that produces a lot of pain but is not associated with any cancerous tumor Fiber: There are several types of fiber, the soluble one (ispagula, psyllium) and the insoluble one (wheat bran). In several studies, the effects of different fibers on irritable bowel syndrome were assessed, appreciating that soluble fiber improved symptoms, except bloating and abdominal pain. Insoluble fiber did not show significant improvement.
They are used in cases with a predominance of constipation. They are useful although with limitations.
These are drugs that are used in cases where diarrhea predominates. Within this group, we have drugs with loperamide, codeine, and ion exchange resins. There is no evidence of its usefulness.
These are drugs that act on the smooth muscle fiber of the digestive tract, inhibiting its motility. They usually improve abdominal pain in a high percentage of patients. They are not useful in cases of constipation.
5HT4 serotonin receptor agonists
These medications stimulate intestinal motility and reduce visceral sensitivity, therefore improve intestinal transit and improve pain. They would be indicated in cases of constipation that does not respond to other measures. Multiple molecules have been investigated, most of them have been discontinued or their use has been restricted due to adverse effects, especially at the cardiovascular level. Currently, we have marketed prucalopride, which is used in selected cases.
Linaclotide is a peptide that binds to the guanylate cyclase C receptors of the intestine. This causes a reduction in intestinal sensitivity, reducing abdominal pain and increasing the amount of fluid that occurs at the intestinal level and blocking its absorption, thereby improving intestinal transit. It is used in cases with moderate or severe constipation without response to previous treatment. It has a very good safety profile, being very safe.
They have been used not to regulate mood, but for their mechanism of action at the intestinal level. There are two groups, tricyclic antidepressants, such as amitriptyline, and SSRIs, and those with a more modern and better safety profile, including paroxetine. These medications regulate visceral sensitivity and promote motility.
The role of probiotics is not yet fully demonstrated, but it seems to ease symptoms of IBS such as meteorism and bloating.